What it is
- A short peptide encoded within mitochondrial DNA, first described in 2015.
What researchers have investigated
- Studies have explored its relationship to metabolism and exercise physiology, largely in mice and cell culture.
Type of evidence
- Predominantly preclinical, with early observational human measurements of naturally occurring levels.
What remains unknown
- Whether administering it benefits humans, what doses would be safe, and how findings in mice translate.
Safety & regulatory context
- Not FDA approved for human use. Regulatory status should be verified individually.
Inclusion does not imply availability.
Level Health does not sell, prescribe or recommend MOTS-C. Findings in animals or cells do not establish benefits in people.
Primary sources: PubMed search for MOTS-C. Reviewed by: pending. Last reviewed: pending.